Pentobarbital will decrease the level or outcome of ethotoin by influencing hepatic enzyme CYP2C9/10 metabolism. Use Caution/Check. pentobarbital will lessen the extent or outcome of alosetron by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Unfamiliar. With therapeutic doses of TCAs, barbiturates boost metabolism and decrease blood concentrations of TCAs. pe... https://johni104mwk8.blogdomago.com/profile