At an oral dose of 2000 mg/kg/working day in rats, maternal toxicity and deaths have been observed with an increased incidence of early fetal resorption; spontaneous abortions happened in cynomolgus monkeys with the maternally toxic oral dose of 2000 mg/kg/day; there isn't any ample and effectively-managed trials in pregnant women; https://steved443qcn6.bleepblogs.com/profile