Osteoarthritis can be modeled in mice by destabilization in the medial meniscus by surgically sectioning a ligament from the joint. The CB2 receptor agonist HU308 decreased joint hurt within the DMM osteoarthritis design, whereas CB2 (−/−) mice developed much more joint damage than wild- kind mice (Sophocleous et al, 2015). https://preciousmetalsirareview91221.blognody.com/33923708/thc-concentrates-no-further-a-mystery