These conclusions elevate some questions on the regulation of caspase activation. Why are two cleavage situations needed to take out the prodomain? Our details reveal the cleavage at D9 is required for cleavage at D28. A single achievable explanation is recognition and binding from the D9 website orients the prodomain https://cucurbitacine33209.jts-blog.com/27684816/not-known-facts-about-ch-223191